RDoc is the default documentation tool. The RDoc syntax is the default one allowed inside Ruby files and libraries.
You might find TextTile or Markdown used outside Ruby classes for text files such as the README or the CHANGELOG files. But this isn't the standard sintax so you would need a way to tell the parser which syntax the file is written with, usually this way is the file extension.
GitHub, for example, follows exactly this convenction. Unless a .textile or .markdown extension is specified, the file is parsed as RDoc.
Remember: AFAIK, inline documentation is always parsed as RDoc.