The Popen object is effectively just a wrapper for the child processes PID, stdin, stdout, and stderr, plus some convenience functions for using those.
So the question is why do you need access to the Popen object? Do you want to communicate with the child, terminate it, or check whether it's still running?
In any case there is no way reacquire a Popen object for an already running process.
The proper way to approach this is to launch the child as a daemon, like Tobu suggested. Part of the procedure for daemonising a process is to close stdin and stdout, so you cannot use those to talk to the child process. Instead most daemons use either pipes or sockets to allow clients to connect to them and to send them messages.
The easiest way to talk to the child is to open a named pipe from the child process at e.g. /etc/my_pipe, open that named pipe from the parent / controlling process, and write / read to / from it.
After a quick look at python-daemon it seems to me that python-daemon will help you daemonise your child process, which is tricky to get right, but it doesn't help you with the messaging side of things.
But like I said, I think you need to tell us why you need a Popen object for the child process before we can help you any further.