Well, usually hash-functions (and cryptographic functions generally) work on bytes. The Python strings are basically byte-strings. If you want to compute the hash of some object you have to convert it to a string representation. Just make sure to apply the same operation later if you want to check if the hash is correct. And make sure that your string representation doesn't contain any changing data that you don't want to be checked.
Edit: Due to popular request a short reminder that Python unicode strings don't contain bytes but unicode code points. Each unicode code point contains multiple bytes (2 or 4, depending on how the Python interpreter was compiled). Python strings only contain bytes. So Python strings (type str) are the type most similar to an array of bytes.