I am not exactly sure what this is trying to achieve, or what your datamodel looks like, but something like this?
var subs = db.Subscriptions.Where(p => p.PatientID == patID).Where(p => p.MonitoringObject.Category.Name == "Medication");
var targets = subs
.SelectMany(s => s.Targets)
.Where(t => t.Date == t.Subscription.Targets.Max(_t => _t.Date))
AHM
2010-03-17 13:14:49