Tkinter layout question

Answer 1

What you can't see in that picture is the big element D in the third slot of the 3-element hbox that's in the first slot of the 2-element vbox.

Answer 2

Try:

A: row 0, column 0, sticky=W
B: row 0, column 1, sticky=W
C: row 1, column 0, span 3
grid_columnconfigure(2, weight=4)