As Far As I Know there is no standard knowledge about using VB6 to test that your friend is expected to know. If your friend knows testing, and she knows VB6, she should be fine. I'd guess the employer has a special testing method they've invented themselves, and they wouldn't expect the interview candidates to know it in advance. (I could be wrong: we'll see whether anyone else answers this question.)
I did find a book Visual Basic 6 for Testers published in 2001. You can view the table of contents on Amazon. The topics sound a bit wacky - writing unit tests for COM objects through VB6 code, testing databases to see data is valid, checking registry entries are valid with VB6 scripts. I don't think these became standard approaches.