I would agree with everyone here that C is a low-level language where you specify all the tiny details. But I disagree with what everyone is saying about Lisp.
C is a low-level sequential language that is strongly coupled to the von Neumann computer concept (which, in turn, is closely related to Turing machines). C has a lot of syntax; the evil abomination C++ (which isn't really C) is an object-oriented language strongly coupled to C with a whole lot more syntax than C. Both theoretically allow you low-level access to the internals of the computer, but in both, you have to really know what you are doing in order to get the best performance.
To me, performance isn't as much an issue as being able to write code. After all, premature optimization is the root of all evil.
Because C has a lot of syntax, it has a very primitive macro system, which is pretty much limited to text substitution. C++ gets around this by having templates, but because C++ has a lot of syntax, template metaprogramming is a scary thing.
Now, Lisp is a language strongly coupled to the concept of Lambda Calculus--which is one of three ways of viewing a computer (I can't remember what Prolog's method is called, but Prolog's is the third way). In addition, it has very little syntax: a Lisp program is primarily just a bunch of lists, where the first element of each list is treated as a function call unless otherwise noted (usually by using the "quote" operator). Because of this, Lisp has a very powerful macro system--one where you could use the language itself to re-write a program. This, in turn, allows you to mold the language to your needs, which allows you to write programs faster than in a language like C.
As for Lisp being functional, it's not, although Scheme puts special emphasis on functional programming, for educational purposes. Common Lisp has a decidedly non-functional "loop" macro that lets you do all sorts of loopy operations; it is a good example of how you could create a specialized language for your needs. Lisp is whatever you want it to be.