ANCOVA can be done with regression an using dummy variables in the design matrix for the effects that depend on the categorical variable.
A simple example is at
http://groups.google.com/group/pystatsmodels/browse_thread/thread/aaa31b08f3df1a69?hl=en
using the OLS class from scikits.statsmodels
Relevant part of construction of design matrix
xg includes group numbers/labels,
x1 is continuous explanatory variable
>>> dummy = (xg[:,None] == np.unique(xg)).astype(float)
>>> X = np.c_[x1, dummy[:,1:], np.ones(nsample)]
Estimate the model
>>> res2 = sm.OLS(y, X).fit()
>>> print res2.params
[ 1.00901524 3.08466166 -2.84716135 9.94655423]
>>> print res2.bse
[ 0.07499873 0.71217506 1.16037215 0.38826843]
>>> prstd, iv_l, iv_u = wls_prediction_std(res2)
"Test hypothesis that all groups have same intercept"
>>> R = [[0, 1, 0, 0],
... [0, 0, 1, 0]]
>>> print res2.f_test(R)
<F test: F=array([[ 91.69986847]]), p=[[ 8.90826383e-17]],
df_denom=46, df_num=2>
strongly rejected because differences in intercept are very large