Here are some techniques that i would use:
1] Proper Title
Use the Google suggested rules for formatting your documents.
Put the title of your page in H1 tags.
Make sure that the title of your page is the same as the title in your H1 tags.
2] Content
Write GOOD QUALITY content on the subject.
This is already a given since the site is specifically on that subject.
3] Inbound Links
Become a contributor for sites like about.com, mahalo.com etc.
and write short relevant posts on their sites that link back to your main site.
Or you could simply send suggestions to existing contributors on those sites.
Why not write a HOW-TO diagnose Alzheimer for Dummies on Mahalo.com and About.com?
Participate in Discussion forums on that subject and create a link back.
Use a bot to spider forums of WebMD like sites and post generic messages with links
back to your main site.
Example Bot Messages:
Alzheimer is a dreadful disease, see how you can self diagnose Alzheimer on [your site].
Make sure to also add randomized text to the message.
4] Auto Generate Content
This one is tricky, because auto generated content needs to have a decent quality.
This means that your relevant search key words must appear in the content.
The auto generated content links back to your main site for a specific key word.
Auto generated titles looks like: Alzheimer for Dummies, Alzheimers for Elderly,
Self Diagnose Alzheimer. Alzheimer Medicine A, Alzheimer Medicine B etc.
You get the picture.
Write short pieces of text that can be generated as placeholder content in these pages.
Don't make all the pages the same though. Make it look random.
5] Link Farming
Use multiple servers with multiple hosters that are in different IP ranges.
Register your Alzheimer related domains with different hosters under different person/company names.
Auto generate site content on these sites and make sure that they LINK BACK
to your main site.
This basically sets up a Link Farm/Factory
6] Ask a shit load of money
See how serious your client is by asking him a large pot of gold to get him into
the top ten list. Is this feature a must have? Then he should be willing to pay for it.
And use some of that money to crowd source your SEO :D