I am looking for any strategies people use when implementing server applications that service client TCP (or UDP) requests: design patterns, implementation techniques, best practices, etc.
Let's assume for the purposes of this question that the requests are relatively long-lived (several minutes) and that the traffic is time sensitive, so no delays are acceptable in responding to messages. Also, we are both servicing requests from clients and making our own connections to other servers.
My platform is .NET, but since the underlying technology is the same regardless of platform, I'm interested to see answers for any language.