in is the operator you are looking for:
if "cuttlefish" in resp:
print "Response One"
elif "nautilus" in resp:
print "Response Two"
else:
print "Response Three"
in is basically an operator that works on sequences like str, tuple, list. x in y checks if x is part of the sequence y. See also 5.6. Sequence Types in the Python Standard Library documentation.
edit
Regarding your second question “Now, how do I change it so that "cuttlefish" is an entry on cuttlefishList, along with several other entries that should also trigger print "Response One"?”.
That's actually a big more complicated, as you cannot check if any of multiple elements are within a sequence with in. But of course there are possibilities to do this. The simples ist to simply chain all the checks together:
if "cuttlefish" in resp or "someotherfish" in resp or "yetanotherfish" in resp:
print "Response One"
If you have too many different words that would result in that response, then you can also automate that a bit like this:
if any( x in resp for x in ( "cuttlefish", "someotherfish", "yetanotherfish" ) ):
print "Response One"
That is basically a short way of writing (not literally of course, but the idea is the same):
checkList = []
for x in ( "cuttlefish", "someotherfish", "yetanotherfish" ):
checkList.append( x in resp )
if True in checkList:
print "Response One"
So what it does is that it goes through all elements of your tuple and checks for each element x if it is part of the response. It keeps a check list of the results of these checks (in the short form, a generator does this). At the end, you check if True is part of the sequence checkList. If it does, at least one of the fishes were found in the response and you can print the result.
A different way would be to use regular expressions. It might be overkill to use them for a low number of different choices, but on the other hand, you could do great fancy stuff with it.