+1  A: 

So close - what you've got should work, you just have the and syntax wrong in your if condition:

if (!is_admin() && !is_home()) { ....
Pat
There's nothing wrong with that syntax - PHP supports both logical and bitwise operators - the problem is you're most likely using a static front page (see my answer).
TheDeadMedic
@TheDeadMedic - thanks for letting me know.
Pat
+2  A: 
if (!is_admin() && !is_front_page())
    wp_enqueue_script('lightbox', ($stimuli_lightbox_plugin_prefix.$stimuli_lightbox_js),array('scriptaculous-effects'), '1.8');
TheDeadMedic
A: 

Thank you both Pat and TheDeadMedic, problem was still with && !is_home and && !is_fornt_page.

I dont know why but in place where i tried is_home and is_front_page wasn't doing its job, but i found on other page that wraping whole wp_enqueue_script in a function is doing it. So its like this:

function scripts() {
if (!is_admin() && !is_home() ) {
// jquery
global $stimuli_lightbox_plugin_prefix;
global $stimuli_lightbox_js;
wp_enqueue_script('lightbox',     ($stimuli_lightbox_plugin_prefix.$stimuli_lightbox_js), array('scriptaculous-effects'), '1.8');

    }
}
add_action( 'wp_print_scripts', 'scripts'); // now just run the function
Jask