For a number of years I've used Object Role Modeling to design and validate my database schema designs. (The appurtenant software products have been variously named Visiomodeler, Infomodeler, Visual Studio Enterprise Architect ORM Studio, etc.)
It's the only truly conceptual database modeling tool I've ever found to be at all useful; in fact, it's one of few conceptual modeling tools of any kind that I have found useful for actually designing real working software artifacts.
But it now seems to be a fading methodology. Does anyone else remember it, consider it useful, still use it? Note: google for Infomodeler and you can still find a Microsoft link to download a working but unsupported distribution for Windows.
Update with some more references I've come across:
Scott Ambler - Agile Modeling
Scot Becker - Building a Better Data Model
Wikipedia seems to be updating regularly.
Sourceforge has a plugin for Visual Studio.