I will put my vote in for CakePHP (http://www.cakephp.org). It has the ability to manage everything very nicely.
Template
This will allow you to create the base template / layout for the site. It is the main body of the site. You can store multiple layouts all in the views/layouts
directory. You can identify what layout you want to use for any given page within the site.
Static Content
If you have static content pages, they all reside in views/pages
. These will load into the layout wherever you put the <?php echo $content_for_layout; ?>
.
Custom Code
Many times, you will have custom code that may not fit in the framework. No worries, you can add this to the libs
or vendors
folders and call the functionality from there.
Speedy Upgrade Via Bake
One of the cool features of cake is the bake feature. Once you have added your schema to the database, you can use bake to have CakePHP write all of the models (with relationships), the controllers (with basic CRUD and admin sections), and the views for each action within the controller.
Cake has been a great fit for all of the projects I have worked on. It keeps the code well organized, has a very active community, and their documentation is very well written and understandable.
UPDATE: For additional information about some sites who use cakephp you can see a sample list here: http://book.cakephp.org/view/510/Sites-in-the-wild
A few notable (high traffic sites) would be:
https://addons.mozilla.org
http://scratch.mit.edu/