/(?![a-z]+:)/
Anyone knows?
according to Regex Buddy (a product i highly recommend):
Assert that it is impossible to match the regex below starting at this position (negative lookahead) «(?![a-z]+:)»
   Match a single character in the range between “a” and “z” «[a-z]+»
      Between one and unlimited times, as many times as possible, giving back as needed (greedy) «+»
   Match the character “:” literally «:»
the / are delimiters.
?! is negative lookahead.
[a-z] is a character class (any character in the a-z range)
+ is one-or-more times of the preceding pattern ([a-z] in this case)
: is just the colon literal
It roughly means "look ahead and make sure there are no alpha characters followed by a colon".
This regex would make more sense if it had a start of string anchor: /^(?![a-z]+:/, so it wouldn't match abc: (like one of the other answers say), but without the (^) I don't  know how useful this is.
(?!REGEX) is the syntax for negative lookahead. Check the link for an explanation of lookaheads.
The regex fails if the pattern [a-z]+: appear in the string from the current position. If the pattern is not found, regex would succeed, but won't consume any characters. 
It would match 123: or abc but not  abc:
It would match the : in abc:.