I'm getting a "The remote certificate is invalid according to the validation procedure" exception message with the following code:
ServicePointManager.ServerCertificateValidationCallback = new RemoteCertificateValidationCallback(MyCertValidationCb);
var request = (FtpWebRequest)WebRequest.Create(new Uri(myUri));
request.EnableSsl = true;
request.Method = WebRequestMethods.Ftp.UploadFile;
request.BeginGetRequestStream(EndGetStreamCallback, _state);
public static bool MyCertValidationCb(object sender, X509Certificate certificate, X509Chain chain, SslPolicyErrors sslPolicyErrors)
{
    if ((sslPolicyErrors & SslPolicyErrors.RemoteCertificateChainErrors)
              == SslPolicyErrors.RemoteCertificateChainErrors)
    {
        return false;
    }
    if ((sslPolicyErrors & SslPolicyErrors.RemoteCertificateNameMismatch)
        == SslPolicyErrors.RemoteCertificateNameMismatch)
    {
        Zone z;
        z = Zone.CreateFromUrl(((FtpWebRequest)sender).RequestUri.ToString());
        if (z.SecurityZone == SecurityZone.Intranet
            || z.SecurityZone == SecurityZone.MyComputer)
        {
            return true;
        }
        return false;
    }
    return false;
} 
The ftp server is filezilla. FTP over SSL is enabled, and Allow explicit FTP over TLS is also enabled. I've generated a certificate.crt file. Connected to the ftp location using filezilla client, and checked "Always trust this certificate" in the popup window.
In the MyCertValidationCb method, (sslPolicyErrors & SslPolicyErrors.RemoteCertificateChainErrors) == SslPolicyErrors.RemoteCertificateChainErrors is always true.
If I change MyCertValidationCb to always return true, the ftp request goes through without a problem. I'm sure it's an issue with certificates. Anyone have any ideas?