Turns out I can create a recordSet to do this. Unlike, Remou's answer though we don't have to invoke a heavy weight odbc process on our sheet.
The following function (adapted from Mark Nold's answer) will create a record set from the supplied range. It assumes column headers are in the first row of the supplied range. This can be made more robust but its a good starting spot
Function CreateRecordSet(rSource As range) As Recordset
' Constants
Const MAX_CHARS = 1200
' Declarations
Dim rs As Recordset
Dim c As Long
Dim r As Long
Dim colCount As Long
Dim rowCount As Long
Dim fldName As String
colCount = rSource.Columns.Count
rowCount = rSource.rows.Count
' Setup record set
Set rs = New Recordset
r = 1 ' assume first row contains headers
For c = 1 To colCount
fldName = rSource.Cells(r, c).Value
rs.Fields.Append fldName, adVarChar, MAX_CHARS
Next c
' Fill record set
rs.Open
r = 2 ' skip header row
For r = 2 To rowCount
rs.AddNew
Debug.Print "row "; r & " of " & rowCount & " created"
For c = 1 To colCount
rs.Fields(c - 1) = CStr(rSource.Cells(r, c).Value)
Debug.Print "-- row(" & r; "): added col " & c & " of " & colCount
Next c
Next r
Set CreateRecordSet = rs
End Function
Sub TestCreateRecordSet()
Dim r As range
Dim rs As Recordset
Set r = range("A1:B4")
Set rs = CreateRecordSet(r)
End Sub