As the founder of OpenQA and Selenium RC, I'm obviously biased towards Selenium as a good option. We recently just put out a 1.0 beta 2 release and are very close to a 1.0 final.
However, you couldn't go wrong with Watir/FireWatir either. Adam's comment that WebDriver will merge to form Selenium 2.0 is correct, but he's incorrect in implying that Watir doesn't use native hooks. If Watir were simply a Selenium clone and also used JavaScript injection, I'd say it wasn't worth looking at.
But because it has native hooks, it can do some things that Selenium currently can't. While it has fewer browsers supported, it goes a bit deeper in the main browser it does support (IE) and lets you control things outside of the page/canvas.
In summary: either is fine, Selenium is great, and if you hang on a little longer with Selenium you'll soon get the best of both worlds with WebDriver/Selenium 2.0.