This has happened repeatedly on various machines in VS2008 and Visual C# 2008.
I create an XBAP appliation.
I click the green arrow and it works.
I click Build/Publish and publish it to either a website or folder, it works.
I make some changes, publish again, and I just get a white screen. Both browsers, can restart, always blank.
It seems to be some kind of caching, etc. Has anyone had this happen to them and found a workaround?