Looking through all the reflector code, nothing pops up as the "right" way.
However, there might be a way if you are willing to do some post-generation processing.
Using the RegionDirective, place a special token in the RegionText value. Then, once your code is generated, go back and do a string replace.
Since I didn't see anything in the code that enforces matching code regions, you could have a single start code region at the end to enable warnings again.
For example. your tokens could be "#PRAGMA1591" and "#ENABLEWARNINGS." Therefore, after the code is generated you would have
#region #PRAGMA1591
...
#region #WARNINGRESTORE
#endregion
You would then do a string replace to yield this:
#region Disable Warning 1591
#pragma warning disable 1591
...
#pragma warning restore
#endregion
Your strings expand like this:
- #PRAGMA1591 -> Ignore Lack of XML Documentation \n #pragma warning
disable 1591
- #region #WARNINGSRESTORE -> #pragma warning restore