You can solve this with a program exactly the same way you solve it by hand (with multiplication and subtraction, then feeding results back into the equations). This is pretty standard secondary-school-level mathematics.
-44.3940 = 50a + 37b + c (A)
-45.3049 = 43a + 39b + c (B)
-44.9594 = 52a + 41b + c (C)
(A-B): 0.9109 = 7a - 2b (D)
(B-C): 0.3455 = -9a - 2b (E)
(D-E): 1.2564 = 16a (F)
(F/16): a = 0.078525 (G)
Feed G into D:
0.9109 = 7a - 2b
=> 0.9109 = 0.549675 - 2b (substitute a)
=> 0.361225 = -2b (subtract 0.549675 from both sides)
=> -0.1806125 = b (divide both sides by -2) (H)
Feed H/G into A:
-44.3940 = 50a + 37b + c
=> -44.3940 = 3.92625 - 6.6826625 + c (substitute a/b)
=> -41.6375875 = c (subtract 3.92625 - 6.6826625 from both sides)
So you end up with:
a = 0.0785250
b = -0.1806125
c = -41.6375875
If you plug these values back into A, B and C, you'll find they're correct.
The trick is to use a simple 4x3 matrix which reduces in turn to a 3x2 matrix, then a 2x1 which is "a = n", n being an actual number. Once you have that, you feed it into the next matrix up to get another value, then those two values into the next matrix up until you've solved all variables.
Provided you have N distinct equations, you can always solve for N variables. I say distinct because these two are not:
7a + 2b = 50
14a + 4b = 100
They are the same equation multiplied by two so you cannot get a solution from them - multiplying the first by two then subtracting leaves you with the true but useless statement:
0 = 0 + 0