I'm running Visual Studio 2008 Professional SP1 on Windows 7 Ultimate x64 RTM. I'm using the ASP.NET MVC that you get from the Web Platform Installer.
When I step through my program and pause on any line for longer than a few seconds the debugger suddenly stops and the following message is printed in the Debug Output:
The program '[4232] WebDev.WebServer.EXE: Managed' has exited with code 0 (0x0).
It does not happen 100% of the time, but it's often enough to be extremely frustrating. This behavior happened in the W7 RC releases as well but never under Windows XP Pro x86.