I heard Joel and Jeff talking about sIFR in one of the early podcasts. I've been using it on www.american-data.com and www.chartright.us with some fairly mixed results.
Yesterday I was informed that the first line of text on my website appeared upside down in Internet Explorer 6 without flash player. I'm pretty sure that assessment was wrong, owing to no flash player = no sIFR. But I'm getting some odd behavior on my pages, at least in IE 6, 7 and 8. I only really wanted to use sIFR because my fonts looked crummy on my computer in Firefox.
My question is: if you use sIFR, when do you use sIFR? In which cases do you disable sIFR? When is it better to just use the browser font?