I don't think this can be done in a single query. You may need some plsql to first test what columns contain data and put together a statement based on that information. Of course, if the data in your table changes you have to recreate the statement.
declare
l_table varchar2(30) := 'YOUR_TABLE';
l_statement varchar2(32767);
l_test_statement varchar2(32767);
l_contains_value pls_integer;
-- select column_names from your table
cursor c is
select column_name
,nullable
from user_tab_columns
where table_name = l_table;
begin
l_statement := 'select ';
for r in c
loop
-- If column is not nullable it will always contain a value
if r.nullable = 'N'
then
-- add column to select list.
l_statement := l_statement || r.column_name || ',';
else
-- check if there is a row that has a value for this column
begin
l_test_statement := 'select 1 from dual where exists (select 1 from ' || l_table || ' where ' ||
r.column_name || ' is not null)';
dbms_output.put_line(l_test_statement);
execute immediate l_test_statement
into l_contains_value;
-- Yes, add column to select list
l_statement := l_statement || r.column_name || ',';
exception
when no_data_found then
null;
end;
end if;
end loop;
-- create a select statement
l_statement := substr(l_statement, 1, length(l_statement) - 1) || ' from ' || l_table;
end;