I use Windows 7 64-bit with 4 GB RAM to run a Windows Virtual PC Guest with Windows 2008 Server, Visual Studio 2008 SP1/Resharper 4.5 and SQL Server 2008. The guest has 2 GB RAM allocated.
Sometimes certain keys stop working in the VS IDE, most often the arrow keys, backspace and enter. The keys still works in Windows and other applications. Restarting VS seems to be the only solution. I've read some suggestions about not using the auto-hide toolbars/windows, but it doesn't seem to work.