FYI WordPress 3.0 is coming out very soon, (it's in beta) and it adds a lot of API for adding custom post types (akin to Drupal nodes). You can actually do it already in WP 2.9, but 3.0 makes it easier to do.
Beyond that, what do you need to make it a CMS? Pages are quite flexible if you use templates. The answer to your question depends a lot on what you want to do in particular.
I recently did a Page-only site (no "posts" section) using just the PageMash plugin. PageMash lets you organize your pages easily (put them in order), and it lets you hide certain pages. So I set the "posts" page to a particular page and then hid that page via PageMash. Create all the pages you like and organize them at will. Works nicely.