First off how do you represent the road?
I recently done exactly this thing and I used Catmull-Rom splines for the road. To orient an object and make it follow the spline path you need to interpolate the current x,y,z position from a t that walks along the spline, then orient it along the Frenet Coordinates System or Frenet Frame for that particular position.
Basically for each point you need 3 vectors: the Tangent, the Normal, and the Binormal. The Tangent will be the actual direction you will like your object (car) to point at.
I choose Catmull-Rom because they are easy to deduct the tangents at any point - just make the (vector) difference between 2 other near points to the current one. (Say you are at t, pick t-epsilon and t+epsilon - with epsilon being a small enough constant).
For the other 2 vectors, you can use this iterative method - that is you start with a known set of vectors on one end, and you work a new set based on the previous one each updateframe() ).