It's not very clear to me what is it exactly that you're looking for but as far as I know ClickOnce it not meant to be used to deploy VC++ applications.
See ClickOnce Deployment For Visual C++
Edit:
There's one thing that jumps out at me in your code example: You have not escaped the "\" character (which is a special character in C++) and in which case the path you supplied would be invalid. Please re-try it like this:
// .. rest of code in your sample ommited
app.StartInfo->FileName = "C:\\INFORME\\SRIMedico.application";
// .. rest of code in your sample ommited
Another thing that I overlooked earlier is that while you may use System::Diagnostics::Process to launch a ClickOnce application installer, it only works using the location where you originally installed the application from, not the location where the application was installed. See the Remarks section in the Process.StartInfo documentation.
You may also use the .appref-ms application reference file to launch the application, if you have it installed on the computer. Assuming this file is located in C:\INFORME\ you may write something like this:
System::Diagnostics::Process^ app = gcnew System::Diagnostics::Process()
app->StartInfo->FileName = "C:\\INFORME\\SRIMedico.appref-ms";
app->StartInfo->Arguments = "";
app->StartInfo->CreateNoWindow = "false";
app->Start();
I hope this helps!