@Brad Tutterow
The exception is not being lost in the first case, it is being passed in to the constructor. I will agree with you on the rest though, the second approach is a very bad idea because of the loss of stack trace. When I worked with .NET, I ran into many cases where other programmers did just that, and it frustrated me to no end when I needed to see the true cause of an exception, only to find it being rethrown from a huge try block where I now have no idea where the problem originated.
I also second Brad's comment that you shouldn't worry about the performance. This kind of micro optimization is a HORRIBLE idea. Unless you are talking about throwing an exception in every iteration of a for loop that is running for a long time, you will more than likely not run into performance issues by the way of your exception usage.
Always optimize performance when you have metrics that indicate you NEED to optimize performance, and then hit the spots that are proven to be the culprit.
It is much better to have readable code with easy debugging capabilities (IE not hiding the stack trace) rather than make something run a nanosecond faster.
A final note about wrapping exceptions into a custom exception... this can be a very useful construct, especially when dealing with UIs. You can wrap every known and reasonable exceptional case into some base custom exception (or one that extends from said base exception), and then the UI can just catch this base exception. When caught, the exception will need to provide means of displaying information to the user, say a ReadableMessage property, or something along those lines. Thus, any time the UI misses an exception, it is because of a bug you need to fix, and anytime it catches an exception, it is a known error condition that can and should be handled properly by the UI.