I build websites for a small-ish media company. Unfortunately, around 45-50% of our client base uses IE6, while the other half are pretty much equally split between Firefox and Webkit-based browsers, with a sprinkling of Opera users.
I start every one of my sites with a reset stylesheet similar to Eric Meyer's, with a few modificaions. I've been using the Blueprint CSS "framework" a lot recently, and it's made my life a lot easier, though I am not especially attached to it.
Roughly 60% of my development time is spent making sure the sites I create don't look incredibly different in each browser. I code for Firefox 3 then tweak from there.
Does anyone know of any stylesheets/frameworks out there that attempt to preemptively account for all of those stupid little browser quirks? I know that nothing out there can totally account for all the browser weirdness, but it would be nice to have something a little more solid to start with.
I'm working on creating my own, but it would be nice to have something to start with.