A simple way to do this in code (and just one of many several ways you could do it):
NSMutableDictionary *dict = [NSMutableDictionary dictionary];
[dict setObject:[NSArray arrayWithObjects:@"a", @"b", @"c", @"d", nil] forKey:@"letters"];
[dict setObject:[NSArray arrayWithObjects:[NSNumber numberWithInt:1], [NSNumber numberWithInt:2], [NSNumber numberWithInt:3], [NSNumber numberWithInt:4], nil] forKey:@"numbers"];
That creates an NSDictionary with an array of strings and an array of NSNumber objects, there are other ways to create arrays, but that demonstrates a basic way to do it.
Per the comments below:
If you wanted to add items to the arrays one at a time...
// create the dictionary and add the letters and numbers mutable arrays
NSMutableDictionary *dict = [NSMutableDictionary dictionary];
NSMutableArray *letters = [NSMutableArray array];
NSMutableArray *numbers = [NSMutableArray array];
[dict setObject:letters forKey:@"letters"];
[dict setObject:numbers forKey:@"numbers"];
// add a letter and add a number
[[dict objectForKey:@"letters"] addObject:@"a"];
[[dict objectForKey:@"numbers"] addObject:[NSNumber numberWithInt:1]];
// This now has an NSDictionary (hash) with two arrays, one of letters and one
// of numbers with the letter 'a' in the letters array and the number 1 in
// the numbers array