Does it have to be pure html?
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A:
Both run modified webkit (the base of chrome and safari) based browsers. They're capable of running full javascript. You'll want to avoid using any browser plugins (like flash) since they're not really supported on these platforms.
They other big concern is the layout. They don't have as much screen space as a typical computer screen and they don't have the same type of input devices. Avoid requiring users to type a lot if it's not required.
Some Andriod phones and the iPhone also support HTML 5 so you can use its capabilities.
Tom Kiley
2010-04-02 15:24:04