Performance on a modern CPU is far from trivial. Here are a couple of things that complicate it:
- Computers are fast. Your CPU can execute upwards of 6 billion instructions per second. So even the slowest instruction can be executed millions of times per second, meaning that it only really matters if you use it very often
- Modern CPU's have hundreds of instructions in flight simultaneously. They are pipelined, meaning that while one instruction is being read, another is reading from registers, a third one is executing, and a fourth one is writing back to a register. Modern CPU's have 15-20 of such stages. On top of this, they can execute 3-4 instructions at the same time on each of these stages. And they can reorder these instructions. If the multiplication unit is being used by another instruction, perhaps we can find an addition instruction to execute instead, for example. So even if you have some slow instructions mixed in, their cost can be hidden very well most of the time, by executing other instructions while waiting for the slow one to finish.
- Memory is hundreds of times slower than the CPU. The instructions being executed don't really matter if their cost is dwarfed by retrieval of data from memory. And even this isn't reliable, because the CPU has its own onboard caches to attempt to hide this cost.
So the short answer is "don't try to outsmart the compiler". If you are able to choose between two equivalent expressions, the compiler is probably able to do the same, and will pick the most efficient one. The cost of an instruction varies, depending on all the above factors. Which other instructions are executing, what data is in the CPU's cache, which precise CPU model is the code running on, and so on. Code that is super efficient in one case may be very inefficient in other cases. The compiler will try to pick the most generally efficient instructions, and schedule them as well as possible. Unless you know more than the compiler about this, you're unlikely to be able to do a better job of it.
Don't try such microoptimizations unless you really know what you're doing. As the above shows, low-level performance is a ridiculously complex subject, and it's very easy to write "optimizations" that result in far slower code. Or which just sacrifice readability on something that makes no difference at all.
Further, most of your code simply doesn't have a measurable impact on performance.
People generally love quoting (or misquoting) Knuth on this subject:
We should forget about small efficiencies, say about 97% of the time: premature optimization is the root of all evil
People often interpret this as "don't bother trying to optimize your code". If you actually read the full quote, some much more interesting consequences should become clear:
Most of the time, we should forget about microoptimizations. Most code is executed so rarely that optimizations won't matter. Keeping in mind the number of instructions a CPU can execute per second, it is obvious that a block of code has to be executed very often for optimizations in it to have any effect. So about 97% of the time, your optimizations will be a waste of time. But he also says that sometimes (3% of the time), your optimizations will matter. And obviously, looking for those 3% is a bit like looking for a needle in a haystack. If you just decide to "optimize your code" in general, you're going to waste your time on the first 97%. Instead, you need to first locate the 3% that actually need optimizing. In other words, run your code through a profiler, and let it tell you which code takes up the most CPU time. Then you know where to optimize. And then your optimizations are no longer premature.