According to "What every programmer should know about memory", by Ulrich Drepper you can do the following on Linux:
Once we have a formula for the memory
requirement we can compare it with the
cache size. As mentioned before, the
cache might be shared with multiple
other cores. Currently {There
definitely will sometime soon be a
better way!} the only way to get
correct information without hardcoding
knowledge is through the /sys
filesystem. In Table 5.2 we have seen
the what the kernel publishes about
the hardware. A program has to find
the directory:
/sys/devices/system/cpu/cpu*/cache
This is listed in Section 6: What Programmers Can Do.
He also describes a short test right under Figure 6.5 which can be used to determine L1D cache size if you can't get it from the OS.
There is one more thing I ran across in his paper: sysconf(_SC_LEVEL2_CACHE_SIZE)
is a system call on Linux which is supposed to return the L2 cache size although it doesn't seem to be well documented.