Speed is always relevant unless your language is useless. If it's useful, people are going to try to use it to do some heavy lifting, and if it doesn't fall on its face when they try, that's always better. This doesn't mean that it is worthwhile to optimize for speed (that depends on your goals), nor does it tell you how (e.g. fast compilation to bytecode vs. reworking how you access a high-level library written in C so that the interpreter has even less to do before calling it).
The optimal balance between speed and abstraction depends on the types of problems being solved. Computer time is generally less valuable than people's time, but both are worth something. Neglecting computer time entirely, it's still useful to consider how much time will be taken total by people working and waiting for results; users of the language ought to be maximally happy when the total coding + execution time is minimized. (Weight by salaries of coders vs. users if you want to make a maximally strong business case.)
Because of the previous two points, I think it's a bad idea for interpreted languages to completely ignore performance. Of course, if the language is experimental itself, you have to ask yourself how much time you want to spend working on performance instead of adding features. It can be okay for an initial implementation to be horribly slow if it will be gradually optimized as it is used more frequently and for more demanding tasks. JavaScript is an excellent example of this.