First rule:
- Don't fetch huge amounts of data back to the application.
Unless you are going to display every single one of the items in the huge amount of data, do not fetch it. Communication between the DBMS and the application is (relatively) slow, so avoid it when possible. It isn't so slow that you shouldn't use the DBMS or anything like that, but if you can reduce the amount of data flowing between DBMS and application, the overall performance will usually improve.
Often, one easy way to do this is to list only those columns you actually need in the application, rather than using 'SELECT *' to retrieve all columns when you'll only use 4 of the 24 that exist.
Second rule:
- Try to ensure that the DBMS does not have to look at huge amounts of data.
To the extent possible, minimize the work that the DBMS has to do. It is busy, and typically it is busy on behalf of many people at any given time. If you can reduce the amount of work that the DBMS has to do to process your query, everyone will be happier.
Consider things like ensuring you have appropriate indexes on the table - not too few, not too many. Designed judiciously, indexes can greatly improve the performance of many queries. Always remember, though, that each index has to be maintained, so inserts, deletes and updates are slower when there are more indexes to manage on a given table.
(I should mention: none of this advice is specific to Oracle - you can apply it to any DBMS.)